Anolis wattsi is a moderate sized anole, measuring up to 58 mm from snout to tail-base (Daltry, 2009). Colour is variable including tan, brown, grey-brown, olive or blue-green, with or without faint dark bands. The male snout often has an orange hue; males also have a white, yellow or orange dewlap with pale blue or white scales (Daltry, 2009). Females are generally less colourful being rich brown or grey-brown, usually with a pale grey stripe down the spine, often bordered with a darker colour and a white stripe running down the side, continuous with the white throat (Daltry, 2009). They are also smaller, reaching up to 46 mm from snout to tail-base (Daltry, 2009). Males often perch 60 cm above the ground, while females and juveniles are often found lower, frequently at ground level (Daltry, 2009). A. wattsi is capable of reaching remarkably high densities with 7,143 / ha reported on Great Bird Island, Antigua (Daltry, 2007) and 7,200 / ha from Anse la Raye, St. Lucia (Daltry, 2009). It is capable of breeding rapidly and is very adaptable, which may assist it in filling vacant, novel territories such as buildings and ornamental grounds (Dalty, 2009).

Three subspecies of Anolis wattsi have been described. A. w. forresti Barbour, 1923, A. w. schwartzi Lazell, 1972, and A. w. wattsi Boulenger, 1894 (Reptiles Database, 2010). A fourth subspecies A. w. pogus has since been elevated to full species status, while the status of A. w. forresti remains unclear (Powell & Henderson, 2001; in Reptiles Database, 2010). Anolis wattsi forresti is endemic to Barbuda with some considering it a separate species (Daltry, 2007).

Anolis wattsi can often be found on or near buildings, bridges or other man-made structures (Daltry, 2009). They are usually found in lowland areas, but have been reported up to 259 m above sea level at Millet, S. Lucia. (Daltry, 2009).

The female Anolis wattsi lays and buries one or two eggs in a shallow nest in the soil (Daltry, 2009).

The diet of Anolis wattsi is varied and includes invertebrates such as ants, spiders, crickets, cockroaches, grasshoppers, and insect larvae, usually caught on the ground as well as soft fruits including mangoes (Daltry, 2009). They often perch close to the ground on tree, walls and other vantage points, scanning the ground for prey (Daltry, 2009).

Anolis wattsi can be dispersed as a stowaway in shipments for agricutural or horticultural trade (White & Hailey, 2006).

As a rapid breeding, adaptive species which is known to reach high densities, Anolis wattsi is capable of displacing native Anolis species (Daltry, 2009). Evidence suggesting this was found by Daltry (2009); indications of the displacement of A. luciae from urban, suburban and some localized, disturbed, secondary forest sites on St. Lucia.
Other potential threats also include competition with the native A. chrysolepis on Trinidad (White & Hailey, 2006), and altering invertebrate populations when present in high densities (Daltry, 2009).

Physical control: While eradications may be unfeasible for widespread Anolis wattsi invasions on islands such as St. Lucia, Daltry (2009) suggests that hand removal may be successful for local control.

Chemical control: Daltry (2009) states that Anolis wattsi is adversely affected by heavy pesticide use on St. Lucia such as those used for agricultural purposes.

Biological control: On St. Lucia, A. wattsi is probably preyed upon by mongoose (Herpestes javanicus) and other invasive predators, however this has not been enough to significantly impact abundance (Daltry, 2009).

Cultural control: Due to the limitations of current control technologies, the spread of A. wattsi is unlikely to be reversed or contained wihout harming native lizard populations (Daltry, 2009). Daltry (2009) makes several management recommendations for St. Lucia to prevent the spread of A. wattsi to other offshore islands. These include: listing A. wattsi as Unprotected under the Wildlife Protection Act; monitoring the spread of this species and be vigilant for signs that it is invading mature, natural forests; preventing A. wattsi from invading the offshore islands, especially the Maria islands, by screening all boats and baggage; and supporting reptile conservation in other tropical countries by prohibiting, screening and removing anole lizards from exported cargo (Daltry, 2009).