Intraguild predation by H. axyridis, as well as competition, dramatically reduce native coccinellid populations throughout its introduced range (Adriens et al, 2008; Alyokhin & Sewell, 2004; Foley et al, 2009; Hautier et al, 2008; Koch, 2003; Koch & Galvan, 2008; Noia et al, 2008; Ware & Majerus, 2008). The intensity of intraguild predation appears to be inversely related to aphid prey availability (Burgio et al, 2002). It has reduced native ladybird populations and become the dominant aphidophagus species in many parts of the United States, Canada, and Europe (Adriaens et al, 2008; Gardiner et al, 2009; Harmon et al, 2007; Kenis et al, 2008). Impacted species include Adalia bipunctata, Adalia decempunctata, Coccinella transversoguttata, Hippodamia tredecimpunctata, Coccinella septempunctata, and Propylea quatordecimpunctata Aphis monardae, Monarda fistulosa, Aphis asclepiadis, Asclepias syriaca (Adriaens et al, 2008; Alyokhin & Sewell, 2004; Koch & Galvan, 2008). It exhibits a high tolerance for the species-specific alkaloid defenses found in coccinellids and preys on native ladybird eggs and larvae while at the same time the defensive chemistry found in its eggs allows them to avoid intraguild predation (Sloggett & Davis, 2010; Pell et al, 2008). Similar alkenes to those that provide defense for its eggs are deposited within its larval tracks and act as oviposition deterring semiochemicals to other ladybirds (Pell et al, 2008). Additionally, it predates on and reduces aphid populations thereby directly competing with native aphidophagus species (Alyokhin & Sewell, 2004; Hautier et al, 2008; Kenis et al, 2008). H. axyridis may also impact and prey on other species such the monarch butterfly (Danaus plexippus) and chrysomelid Galerucella calmariensis (Koch et al, 2003; Sebolt & Landis, 2004 in Koch & Galvan, 2008).

H. axyridis is a significant pest to fruit production and processing. It is a contaminant and cause of damage to wine grapes. It inhabits wine grape orchards and damages and consumes the sugar rich grapes. H. axyridis is harvested along with the grapes and contaminates them by releasing hemolymph when disturbed or killed which causes an unpleasant odor and taste in the resultant wine (EPPO, 2009; Foley et al, 2009; Galvan et al, 2006; Roy & Roy, 2008). Economic consequences are included as a result of losses on the contaminated wine and/or additional costs of time and labor to control its populations (Galvan et al, 2006). Studies have found H. axyridis problematic to wineries in Switzerland and the Great Lakes and eastern regions of the United States (EPPO, 2009; Galvan et al, 2006). It establishment in other major winery regions in Western Europe, South Africa, and California pose a significant threat to the industry (Galvan et al, 2006). H. axyridis is also reported to be a pest to apple, pear, raspberry, citrus, and potato agriculture (EPPO, 2009; Koch & Galvan, 2008; Roy & Roy, 2008).

Finally, H. axyridis is a nuisance that infests homes and other buildings in large numbers searching for overwintering sites (EPPO, 2009; Foley et al, 2009; Koch & Galvan, 2008). High densities, as many as thousands in a single home, aggregate inside buildings and cause cosmetic damage, and sometimes bite or cause allergic reactions (Kenis et al, 2009; Koch & Galvan et al, 2008; Roy & Wajnberg, 2008). Their hemolymph has a foul odor and may stain or cause damage to carpets, curtains, furniture, and walls. They may also act as a contaminant pest to food service, industry, and research institutions (Koch & Galvan, 2008). Some studies state that it has become an important seasonal allergen in the United States indicating that it can cause symptoms including chronic cough, conjunctivitis, and even asthma (Foley et al, 2009; Koch & Galvan et al, 2008; Pervez & Omkar, 2006).

H. axyridis is a significant pest to fruit production and processing. It is a contaminant and cause of damage to wine grapes. It inhabits wine grape orchards and damages and consumes the sugar rich grapes. H. axyridis is harvested along with the grapes and contaminates them by releasing hemolymph when disturbed or killed which causes an unpleasant odor and taste in the resultant wine (EPPO, 2009; Foley et al, 2009; Galvan et al, 2006; Roy & Roy, 2008). Economic consequences are included as a result of losses on the contaminated wine and/or additional costs of time and labor to control its populations (Galvan et al, 2006). Studies have found H. axyridis problematic to wineries in Switzerland and the Great Lakes and eastern regions of the United States (EPPO, 2009; Galvan et al, 2006). It establishment in other major winery regions in Western Europe, South Africa, and California pose a significant threat to the industry (Galvan et al, 2006). H. axyridis is also reported to be a pest to apple, pear, raspberry, citrus, and potato agriculture (EPPO, 2009; Koch & Galvan, 2008; Roy & Roy, 2008).

Finally, H. axyridis is a nuisance that infests homes and other buildings in large numbers searching for overwintering sites (EPPO, 2009; Foley et al, 2009; Koch & Galvan, 2008). High densities, as many as thousands in a single home, aggregate inside buildings and cause cosmetic damage, and sometimes bite or cause allergic reactions (Kenis et al, 2009; Koch & Galvan et al, 2008; Roy & Wajnberg, 2008). Their hemolymph has a foul odor and may stain or cause damage to carpets, curtains, furniture, and walls. They may also act as a contaminant pest to food service, industry, and research institutions (Koch & Galvan, 2008). Some studies state that it has become an important seasonal allergen in the United States indicating that it can cause symptoms including chronic cough, conjunctivitis, and even asthma (Foley et al, 2009; Koch & Galvan et al, 2008; Pervez & Omkar, 2006).

Chemical: Traps utilizing pheromone and semiochemical lures are being investigated (Kenis et al, 2008). Exterior application of insecticides focused around windows, doors, foundations, and eves may be prevent infestation by H axyridis (Koch, 2003; Koch & Hutchison, 2003b). Most insecticides commonly used in agricultural environments are toxic to H. axyridis (Kenis et al, 2008). DEET (N,N-diethyl-3-methylbenzamide) and repellents camphor and menthol have also been found to be effective (Koch & Galvan, 2008).
Insecticide treatment of H. axyridis in vineyards should not be done preventively but an integrated pest management program should be based on the timing of infestation, estimated levels of infestation and resulting taint, and control methods. H. axyridis adults begin to move to grape clusters between 2 and 3 weeks prior to harvest. Even though fluctuate during the growing season, grape growers should not act until 2 or 3 weeks before harvest when the proportion of injured berries increases, which then attracts and provides opportunity for H. axyridis to feed on the grapes. Grape growers can follow H. axyridis population fluctuation in vineyards using yellow sticky traps, which can be used as an early warning. Control measures to manage H. axyridis before it can become a wine contaminant are essential for reducing the economic impact of this pest on the wine industry. In field and laboratory studies, carbaryl, bifenthrin, zeta-cypermethrin, thiamethoxam, and imidacloprid showed either toxic and/or repellent effects. However, of these insecticides, only carbaryl, thiamethoxam and imidacloprid are currently labeled in the United States for use on wine grapes within 7 days of harvest, which is when H. axyridis typically reaches high densities (Koch & Galvan, 2008). Some discourage against the use of insecticides in vineyards and orchards because of their effect on native aphidophages and beneficial insects (Roy & Roy, 2008).

Biological control:Several parasitoids attack H. attack including phorids Phalacrotophora philaxyridis and other Phalacrotophora spp., tachinids Degeria lutuosa and Stronygaster trianulifera, and braconid Dinocampus coccinellae but have not been investigated as potential biological controls (Koch, 2003). The entomopathogenic fungus Beauveria bassiana infects H. axyridis and has been found to reduce egg production and cause winter mortality in studies and may hold potential as a biological control (Roy et al, 2008b; Steenberg & Harding, 2009).